How long does it take for the body to get rid of modafinil after taking it? This is called its "elimination time." The half-life of modafinil is usually between 12 and 15 hours. This means that it takes that long for the medication to be half as strong in the body. Modafinil can stay in the body for up to 60 to 75 hours after the last dose because it usually takes five half-lives to c... https://www.medzsquare.com/au/modalert-200